| Response to Letter to the Editor: Comparison of short- and mid-term outcomes of antiplatelet versus anticoagulant use in peripheral artery disease patients with synthetic grafts | ||
| 2025, Vol 12, Num 3 Page(s): 252-252 | ||
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| DOI: 10.5606/e-cvsi.2025.8581 | ||
| Mert Çelik1, Aykut Şahin2 | ||
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1Department of Cardiovascular Surgery, Muş State Hospital, Muş, Türkiye 2Department of Cardiovascular Surgery, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Türkiye |
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We sincerely thank the author for their interest
in and constructive comments on our study.[1] In
this study, we compared the short- and mid-term
outcomes of anticoagulant versus antiplatelet
therapy following above-knee femoropopliteal
bypass with synthetic grafts. We demonstrated
that patency rates were similar between the two
treatment groups.[2]
Considering the potential impact of graft properties and type selection on patency outcomes, our study cohort was limited to patients treated with straight Dacron® grafts. To minimize heterogeneity, we included only patients who underwent bypass with straight Dacron® grafts. Nevertheless, as rightly noted, technical parameters such as graft diameter and configuration may also impact graft patency. Clarification of these factors, however, requires further studies with larger patient cohorts. From an anatomical standpoint, the integrity and patency of distal vessels are pivotal for adequate runoff, particularly in the context of revascularization procedures. We fully concur with this opinion. Accordingly, in our study, we selected patients with sufficiently distal runoff for above-knee femoropopliteal bypass, and during follow-up, no additional surgical or endovascular reinterventions were required for infragenicular disease. In conclusion, our study attempted to address a clinically relevant issue frequently encountered in daily vascular practice, yet one for which robust data remain limited. Larger prospective studies are warranted to validate and expand upon our findings. Data Sharing Statement: The data that support the findings of this study are available from the corresponding author upon reasonable request. Author Contributions: All authors contributed equally to this article. Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article. Funding: The authors received no financial support for the research and/or authorship of this article. |
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Çelik M, Şahin A. Response to Letter to the Editor: Comparison of short- and
mid-term outcomes of antiplatelet versus anticoagulant use in peripheral artery
disease patients with synthetic grafts. Cardiovasc Surg Int 2025;12(3):252. doi:
10.5606/e-cvsi.2025.8581.
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