Objectives: This study aims to investigate the effect of Killip class on the development of anxiety and depression in patients admitted to intensive care unit (ICU) with acute myocardial infarction (AMI) and to identify risk groups in terms of anxiety and depression.

Patients and methods: Between May 2024 and October 2024, a total of 200 patients (140 males, 60 females; mean age: 61.4±12.1 years; range, 31 to 89 years) with acute ST elevation MI (STEMI) and non-ST elevation MI (NSTEMI) were included. The Hospital Anxiety and Depression Scale (HADS) was administered within the first 24 h after the patients' treatment in the ICU was completed and the patients were transferred to ward.

Results: Anxiety was observed in 60 (30%) of the patients, while depression was observed in 93 (46.5%) of the patients. A total of 148 (74%) of the patients were Killip in Class I, while the others had a class other than Killip I. Having a class other than Killip I and prolonged ICU stay significantly increased the anxiety scores (p=0.003 and p=0.016). In the univariate and multivariate regression analysis, having a classification other than Killip I was found to be an independent predictor of ICU anxiety (odds ratio [OR]=0.456; 95% confidence interval [CI]: 0.210-0.993; p=0.048).

Conclusion: Killip classification is an independent predictor of anxiety in AMI patients. Since patients with AMI, particularly those who are in Killip Class II-IV, are in the risk group for anxiety, it is of utmost importance to evaluate the anxiety status of these patients as soon as possible and to reduce the affecting factors by identifying them.